Safety handling of magnesium
نویسندگان
چکیده
منابع مشابه
Inherited disorders of renal magnesium handling.
The genetic basis and cellular defects of a number of primary magnesium wasting diseases have been elucidated over the past decade. This review correlates the clinical pathophysiology with the primary defect and secondary changes in cellular electrolyte transport. The described disorders include (1) hypomagnesemia with secondary hypocalcemia, an earlyonset, autosomal-recessive disease segregati...
متن کاملEffects of the EGFR Inhibitor Erlotinib on Magnesium Handling.
A mutation in pro-EGF causes isolated hypomagnesemia, and monoclonal antibodies targeting the extracellular domain of the EGF receptor (EGFR) affect epithelial Mg(2+) transport. The effect of the EGFR tyrosine kinase inhibitor erlotinib on Mg(2+) homeostasis, however, remains unknown. Here, we injected C57BL/6 mice with erlotinib for 23 days and observed a small but significant decrease in seru...
متن کاملDaily magnesium supplements improve glucose handling in elderly subjects.
We demonstrated similar plasma concentrations and urinary losses but lower erythrocyte magnesium concentrations (2.18 +/- 0.04 vs 1.86 +/- 0.03 mmol/L, P less than 0.01) in twelve aged (77.8 +/- 2.1 y) vs 25 young (36.1 +/- 0.4 y), nonobese subjects. Subsequently, aged subjects were enrolled in a double-blind, randomized, crossover study in which placebo (for 4 wk) and chronic magnesium adminis...
متن کاملRenal magnesium handling is not subject to developmental programming.
Developmental programming of hypertension, induced by maternal protein restriction, is associated with enhanced urinary excretion of sodium and calcium in the rat. Although calcium and magnesium are reabsorbed via different pathways, renal calcium excretion often parallels magnesium output. Accordingly, the aim of the current study was to assess magnesium handling in rats exposed to a low-prote...
متن کاملHandling Consistency Between Safety and System Models
Safety analyses are of paramount importance for the development of embedded systems. In order to perform these analyses, safety engineers use different modeling techniques, such as, for instance, Fault Trees or Reliability Block Diagrams. One of the industrial development process challenges today is to ensure the consistency between safety models and system architectures. Model Based Safety Ana...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Japan Institute of Light Metals
سال: 2009
ISSN: 0451-5994,1880-8018
DOI: 10.2464/jilm.59.154